2010986-19-1
2010986-19-1 structure
- Name: VH032-NH-CO-CH2-NHBoc
- Chemical Name: L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]glycyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
- CAS Number: 2010986-19-1
- Molecular Formula: C29H41N5O6S
- Molecular Weight: 587.73
- Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
- Create Date: 2023-03-16 18:25:09
- Modify Date: 2024-01-29 11:29:28
-
VH032-NH-CO-CH2-NHBoc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL to recruit von Hippel-Lindau (VHL) proteins. VH032-NH-CO-CH2-NHBoc will remove the Boc protection under acidic conditions, and connect with the target protein ligand through a linker to form a PROTAC molecule, which is a key intermediate for the synthesis of PROTAC based on VHL ligand.
| Name | L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]glycyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- |
|---|
| Description | VH032-NH-CO-CH2-NHBoc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL to recruit von Hippel-Lindau (VHL) proteins. VH032-NH-CO-CH2-NHBoc will remove the Boc protection under acidic conditions, and connect with the target protein ligand through a linker to form a PROTAC molecule, which is a key intermediate for the synthesis of PROTAC based on VHL ligand. |
|---|---|
| Related Catalog |
| Molecular Formula | C29H41N5O6S |
|---|---|
| Molecular Weight | 587.73 |