1957239-88-1

1957239-88-1 structure
1957239-88-1 structure
  • Name: Onfekafusp Alfa
  • Chemical Name: Onfekafusp Alfa
  • CAS Number: 1957239-88-1
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Research Areas Cancer
  • Create Date: 2023-03-07 08:48:24
  • Modify Date: 2025-11-28 19:31:45
  • Onfekafusp alfa (L19TNF) is a homotrimer that forms from engineered peptides for the L19 antibody in scFv format fused to human TNF. Onfekafusp alfa can be used for malignant glioma research[1][2].

Name Onfekafusp Alfa
Description Onfekafusp alfa (L19TNF) is a homotrimer that forms from engineered peptides for the L19 antibody in scFv format fused to human TNF. Onfekafusp alfa can be used for malignant glioma research[1][2].
Related Catalog
In Vitro Onfekafusp alfa 显示出比 mTNFα 和 TN11mTNFα 更强的抗癌活性[2]。 在 L-M 小鼠成纤维细胞的细胞毒性试验中,Onfekafusp alfa 的活性比等摩尔量的重组 mTNFα 和融合蛋白 TN11mTNFα 高 5 到 6 倍[2]。
References

[1]. Di Giacomo AM, et al. Immunotherapy for brain metastases and primary brain tumors. Eur J Cancer. 2023 Jan;179:113-120.  

[2]. Borsi L, et al. Selective targeted delivery of TNFalpha to tumor blood vessels. Blood. 2003 Dec 15;102(13):4384-92.  

No Any Chemical & Physical Properties
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.