2283356-07-8

2283356-07-8 structure

2283356-07-8 structure

Name: Letaplimab
Chemical Name: Letaplimab
CAS Number: 2283356-07-8
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Cancer
Create Date: 2023-02-26 02:27:35
Modify Date: 2024-04-07 17:23:53
Letaplimab (IBI-188) is a humanized IgG4 anti-CD47 monoclonal antibody. CD47 is overexpressed on cancer cells, it is a ligand for SIRPα. Letaplimab enhances tumor cell phagocytosis[1].

Name	Letaplimab

Description	Letaplimab (IBI-188) is a humanized IgG4 anti-CD47 monoclonal antibody. CD47 is overexpressed on cancer cells, it is a ligand for SIRPα. Letaplimab enhances tumor cell phagocytosis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Miao Miao, et al. A Phase 1b Study to Evaluate Safety and Efficacy of IBI188 in Combination with Azacitidine (AZA) As a First-Line Treatment in Subjects with Newly Diagnosed Higher Risk Myelodysplastic Syndrome. MYELODYSPLASTIC SYNDROMES-CLINICAL AND EPIDEMIOLOGICAL NOVEMBER 15, 2022.

No Any Chemical & Physical Properties