1349197-90-5
1349197-90-5 structure
- Name: di-Pal-MTO
- Chemical Name: di-Pal-MTO
- CAS Number: 1349197-90-5
- Molecular Formula: C54H84N4O8
- Molecular Weight: 917.27
- Catalog: Research Areas Cancer
- Create Date: 2023-04-28 10:07:47
- Modify Date: 2025-11-29 18:23:56
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di-Pal-MTO is a palm oil-based lipid produced by combining the anticancer drug mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity[1].
| Name | di-Pal-MTO |
|---|
| Description | di-Pal-MTO is a palm oil-based lipid produced by combining the anticancer drug mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity[1]. |
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| Related Catalog | |
| In Vitro | Delivery of Mcl-1-specific anticancer siRNA (siMcl-1) using nanoparticles of mono-Pal-MTO and di-Pal-MTO (md11-Pal-MTO) in a 1:1 molar ratio enhances in vitro antitumour activity, reducing tumour cell viability by 81% and tumour size by 83%. Lipofectamine 2000-mediated transfection with siMcl-1 reduces tumour cell viability by 68%[1]. |
| References |
| Molecular Formula | C54H84N4O8 |
|---|---|
| Molecular Weight | 917.27 |