2413192-92-2
2413192-92-2 structure
- Name: HBV-IN-30
- Chemical Name: HBV-IN-30
- CAS Number: 2413192-92-2
- Molecular Formula: C22H18BrClO6
- Molecular Weight: 493.73
- Catalog: Signaling Pathways Anti-infection HBV
- Create Date: 2023-04-18 17:46:25
- Modify Date: 2024-04-03 16:09:09
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HBV-IN-30 (ex44), a flavone derivative, is a potent covalently closed circular DNA (cccDNA) inhibitor. cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-30 has the potential for the research of HBV infection[1].
| Name | HBV-IN-30 |
|---|
| Description | HBV-IN-30 (ex44), a flavone derivative, is a potent covalently closed circular DNA (cccDNA) inhibitor. cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-30 has the potential for the research of HBV infection[1]. |
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| Related Catalog | |
| In Vitro | HBV-IN-30 (ex44; 24 h) 在 HepDES19 细胞中抑制 HBeAg 水平和细胞活力，IC50 值为 0.57 μM。HepDES19 是产生 cccDNA 的细胞系[1]。 HBV-IN-30 (5 天) 以剂量依赖性方式降低 HepDES19 细胞中的 cccDNA 水平[1]。 HBV-IN-30 (9 天; 原代人肝细胞 (PHH)) 具有抗 HBV 作用并抑制 HBeAg，IC50 值为 0.04 μM[1]。 |
| References |
| Molecular Formula | C22H18BrClO6 |
|---|---|
| Molecular Weight | 493.73 |