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30408-07-2

30408-07-2 structure
30408-07-2 structure
  • Name: JB002
  • Chemical Name: JB002
  • CAS Number: 30408-07-2
  • Molecular Formula: C18H15NO3
  • Molecular Weight: 293.32
  • Catalog: Signaling Pathways Cytoskeleton Myosin
  • Create Date: 2023-04-09 18:22:49
  • Modify Date: 2025-08-27 13:13:21
  • JB002 is a myosin II inhibitor, with an IC50 of ≤10 μM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy[1].

Name JB002
Description JB002 is a myosin II inhibitor, with an IC50 of ≤10 μM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy[1].
Related Catalog
Target

IC50: ≤10 μM (myosin II)[1]

In Vitro JB002 在心脏和骨骼肌球蛋白之间表现出良好的选择性,但对非肌肉 IIB 没有可检测的活性[1]。
References

[1]. Smith JD, et, al. Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II. Eur J Med Chem. 2022 Dec 12;247:115008.  

Molecular Formula C18H15NO3
Molecular Weight 293.32
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