2414254-51-4

2414254-51-4 structure
2414254-51-4 structure
  • Name: MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
  • Chemical Name: MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
  • CAS Number: 2414254-51-4
  • Molecular Formula: C55H60FN9O13
  • Molecular Weight: 1074.12
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Topoisomerase
  • Create Date: 2023-06-20 08:03:29
  • Modify Date: 2024-01-10 11:16:32
  • MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a drug-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].

Name MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
Description MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a drug-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].
Related Catalog
Target

Topoisomerase I

References

[1]. Ying Hua, et al. Anti-B7H3 antibody-exatecan analog conjugate and medicinal use thereof: World Intellectual Property Organization, WO2020063673[P]. 2020-04-02.

Molecular Formula C55H60FN9O13
Molecular Weight 1074.12