308145-19-9
308145-19-9 structure
- Name: PG-11047
- Chemical Name: PG-11047
- CAS Number: 308145-19-9
- Molecular Formula: C14H32N4
- Molecular Weight: 256.43
- Catalog: Research Areas Cancer
- Create Date: 2023-04-20 14:10:44
- Modify Date: 2024-01-02 18:19:47
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PG-11047 (CGC-11047) is a polyamine analogue. PG-11047 can be used for the research of breast cancer[1].
| Name | PG-11047 |
|---|
| Description | PG-11047 (CGC-11047) is a polyamine analogue. PG-11047 can be used for the research of breast cancer[1]. |
|---|---|
| Related Catalog | |
| In Vitro | PG-11047 (13 nM-5 mM; 72 h) 抑制乳腺细胞系成员的生长，范围很广，基底样细胞系在低于管腔细胞系的浓度下受到抑制[ 1]. PG-11047 (0.3, 10, 300 μM; 48 h, 72 h) 在几乎不产生细胞凋亡的剂量下显示 S 期分数显着降低[1]。 Cell Cycle Analysis[1] Cell Line: Breast cancer cell lines Concentration: 0.3, 10, 300 μM Incubation Time: 48 h, 72 h Result: Significant decreased the fraction of cells in S-phase with increasing doses. Apoptosis Analysis[1] Cell Line: Breast cancer cell lines Concentration: 0.3, 10, 300 μM Incubation Time: 48 h, 72 h Result: Induced apoptosis at high concentrations. |
| References |
| Molecular Formula | C14H32N4 |
|---|---|
| Molecular Weight | 256.43 |