2380273-67-4

2380273-67-4 structure

Name: Pomalidomide-PEG1-NH2-1 hydrochloride
Chemical Name: Pomalidomide-PEG1-NH2-1 hydrochloride
CAS Number: 2380273-67-4
Molecular Formula: C₁₇H₁₉ClN₄O₆
Molecular Weight: 410.81
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2023-04-23 18:17:06
Modify Date: 2024-01-24 16:33:50
Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand[1].

Name	Pomalidomide-PEG1-NH2-1 hydrochloride

Description	Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
References	[1]. Lee B, et al. Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug. J Enzyme Inhib Med Chem. 2023 Dec;38(1):51-66.

Molecular Formula	C₁₇H₁₉ClN₄O₆
Molecular Weight	410.81