890654-03-2

890654-03-2 structure

Name: S-Me-DM4
Chemical Name: S-Me-DM4
CAS Number: 890654-03-2
Molecular Formula: C₃₉H₅₆ClN₃O₁₀S
Molecular Weight: 794.39
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
Create Date: 2023-04-04 17:52:05
Modify Date: 2024-04-06 20:20:33
S-Me-DM4 is a metabolite of DM4 S-methylated by intracellular enzyme. DM4 (HY-100503) is a microtubule-depolymerizing maytansinoid with strong cytotoxicity. DM4 can be used as an ADC Cytotoxin molecule[1].

Name	S-Me-DM4

Description	S-Me-DM4 is a metabolite of DM4 S-methylated by intracellular enzyme. DM4 (HY-100503) is a microtubule-depolymerizing maytansinoid with strong cytotoxicity. DM4 can be used as an ADC Cytotoxin molecule[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
References	[1]. Widdison W, et al. Metabolites of antibody-maytansinoid conjugates: characteristics and in vitro potencies. Mol Pharm. 2015 Jun 1;12(6):1762-73.

Molecular Formula	C₃₉H₅₆ClN₃O₁₀S
Molecular Weight	794.39