923954-79-4

923954-79-4 structure

Name: TAT-HA2 Fusion Peptide
Chemical Name: TAT-HA2 Fusion Peptide
CAS Number: 923954-79-4
Molecular Formula: C₁₄₉H₂₄₃N₅₃O₃₉S
Molecular Weight: 3432.92
Catalog: Signaling Pathways Anti-infection Influenza Virus
Create Date: 2023-06-11 13:14:49
Modify Date: 2024-01-10 17:50:58
TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide induces the cellular uptake of macromolecules into endosomes via the TAT moiety and to respond to the acidifying lumen of endosomes to cause membrane leakage and release of macromolecules into cells via the HA2 moiety[1].

Name	TAT-HA2 Fusion Peptide

Description	TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide induces the cellular uptake of macromolecules into endosomes via the TAT moiety and to respond to the acidifying lumen of endosomes to cause membrane leakage and release of macromolecules into cells via the HA2 moiety[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Others
References	[1]. Ya-Jung Lee, et al. Modeling of the endosomolytic activity of HA2-TAT peptides with red blood cells and ghosts. Biochemistry. 2010 Sep 14;49(36):7854-66.

Molecular Formula	C₁₄₉H₂₄₃N₅₃O₃₉S
Molecular Weight	3432.92