1637253-79-2

1637253-79-2 structure

1637253-79-2 structure

Name: EGFR/HER2-IN-9
Chemical Name: EGFR/HER2-IN-9
CAS Number: 1637253-79-2
Molecular Formula: C₂₅H₂₅ClFN₅O₄
Molecular Weight: 513.95
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2023-04-20 11:09:23
Modify Date: 2024-01-24 16:33:24
EGFR/HER2-IN-9 (Compound 1) is an EGFR and HER2 inhibitor with IC50s of 3.2, 8.3 and 14 nM against EGFR, EGFR T790M and HER2, respectively[1].

Name	EGFR/HER2-IN-9

Description	EGFR/HER2-IN-9 (Compound 1) is an EGFR and HER2 inhibitor with IC50s of 3.2, 8.3 and 14 nM against EGFR, EGFR T790M and HER2, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:3.2 nM (IC50) EGFRT790M:8.3 nM (IC50) HER2:14 nM (IC50)
References	[1]. Yingjun Zhang, et al. Amino quinazoline derivatives as well as salts and application method thereof. Patent CN104119350A.

Molecular Formula	C₂₅H₂₅ClFN₅O₄
Molecular Weight	513.95