2714409-09-1
2714409-09-1 structure
- Name: Ethotoin-d5
- Chemical Name: Ethotoin-d5
- CAS Number: 2714409-09-1
- Molecular Formula: C11H7D5N2O2
- Molecular Weight: 209.26
- Catalog: Research Areas Neurological Disease
- Create Date: 2023-07-08 18:05:02
- Modify Date: 2024-01-21 20:16:55
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Ethotoin-d5 is the deuterium labeled Ethotoin[1]. Ethotoin (Peganone) is an orally active anticonvulsant agent used in epilepsy research, Ethotoin is a hydantoin, similar to phenytoin[2].
| Name | Ethotoin-d5 |
|---|
| Description | Ethotoin-d5 is the deuterium labeled Ethotoin[1]. Ethotoin (Peganone) is an orally active anticonvulsant agent used in epilepsy research, Ethotoin is a hydantoin, similar to phenytoin[2]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| In Vivo | After dosing Ethotoin on gestational day 18, offspring exhibits mild mortality and weight loss[2]. Animal Model: Pregnant Sprague-Dawley CD rats[2] Dosage: 600 mg/kg Administration: Oral gavage, 600 mg/kg, once Result: Preweaning mortality for Ethotoin was 2.0%, Ethotoin -exposed animals weighed approximately 6.6% less than controls. |
| References |
| Molecular Formula | C11H7D5N2O2 |
|---|---|
| Molecular Weight | 209.26 |