2465-91-0
2465-91-0 structure
- Name: Tetra(cyanoethoxymethyl) methane
- Chemical Name: 3-[3-(2-cyanoethoxy)-2,2-bis(2-cyanoethoxymethyl)propoxy]propanenitrile
- CAS Number: 2465-91-0
- Molecular Formula: C17H24N4O4
- Molecular Weight: 348.39700
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-06-06 16:50:19
- Modify Date: 2024-01-02 00:15:55
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Tetra(cyanoethoxymethyl) methane is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-[3-(2-cyanoethoxy)-2,2-bis(2-cyanoethoxymethyl)propoxy]propanenitrile |
|---|---|
| Synonyms | MFCD00053281 |
| Description | Tetra(cyanoethoxymethyl) methane is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.13g/cm3 |
|---|---|
| Boiling Point | 610.6ºC at 760 mmHg |
| Molecular Formula | C17H24N4O4 |
| Molecular Weight | 348.39700 |
| Flash Point | 232ºC |
| Exact Mass | 348.18000 |
| PSA | 132.08000 |
| LogP | 1.69392 |
| Vapour Pressure | 7.54E-15mmHg at 25°C |
| Index of Refraction | 1.479 |
|
~99%
2465-91-0 |
| Literature: Lee, Wai Mun Patent: US2009/112024 A1, 2009 ; Location in patent: Page/Page column 18 ; |
|
~97%
2465-91-0 |
| Literature: FUJIFILM Corporation Patent: US2009/143623 A1, 2009 ; Location in patent: Page/Page column 4 ; |
|
~%
2465-91-0 |
| Literature: Newkome, George R.; Weis, Claus D. Organic Preparations and Procedures International, 1996 , vol. 28, # 2 p. 242 - 244 |
