2762547-06-6

2762547-06-6 structure

Name: CD33 splicing modulator 1 hydrochloride
Chemical Name: CD33 splicing modulator 1 hydrochloride
CAS Number: 2762547-06-6
Molecular Formula: C₂₅H₂₆ClFN₆O
Molecular Weight: 480.96
Catalog: Research Areas Neurological Disease
Create Date: 2023-09-07 12:22:27
Modify Date: 2025-08-27 09:51:53
CD33 splicing modulator 1 (Compound 1) hydrochloride is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. CD33 splicing modulator 1 hydrochloride increases exon 2 skipping in cellular mRNA pools. CD33 splicing modulator 1 hydrochloride has the potential for the research of neurodegenerative disease including Alzheimer's disease[1].

Name	CD33 splicing modulator 1 hydrochloride

Description	CD33 splicing modulator 1 (Compound 1) hydrochloride is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. CD33 splicing modulator 1 hydrochloride increases exon 2 skipping in cellular mRNA pools. CD33 splicing modulator 1 hydrochloride has the potential for the research of neurodegenerative disease including Alzheimer's disease[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Chappie TA, et al. Discovery of Small-Molecule CD33 Pre-mRNA Splicing Modulators. ACS Med Chem Lett. 2022;13(1):55-62.

Molecular Formula	C₂₅H₂₆ClFN₆O
Molecular Weight	480.96