2131025-83-5

2131025-83-5 structure

Name: Cimdelirsen sodium
Chemical Name: Cimdelirsen sodium
CAS Number: 2131025-83-5
Molecular Formula: C₂₉₆H₄₁₅N₈₃Na₂₀O₁₅₂P₂₀S₁₅
Molecular Weight: 9128.16
Catalog: Research Areas Others
Create Date: 2023-06-26 07:26:04
Modify Date: 2025-11-26 13:55:37
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

Name	Cimdelirsen sodium

Description	Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
Related Catalog	Research Areas >> Others
References	[1]. Bhanot S, Fleseriu M, Geary R, et al. OR27-4 Placebo-Controlled and Open-Label Extension Study of a Novel Hepatic-Targeted Antisense Cimdelirsen (IONIS-GHR-LRx) Under Investigation in Acromegaly Patients. J Endocr Soc. 2022;6(Suppl 1):A526.

Molecular Formula	C₂₉₆H₄₁₅N₈₃Na₂₀O₁₅₂P₂₀S₁₅
Molecular Weight	9128.16