2304692-48-4

2304692-48-4 structure

Name: Donidalorsen
Chemical Name: Donidalorsen
CAS Number: 2304692-48-4
Molecular Formula: C₂₉₆H₄₃₅N₈₃O₁₅₁P₂₀S₁₅
Molecular Weight: 8672.64
Catalog: Research Areas Others
Create Date: 2023-06-15 18:55:20
Modify Date: 2025-08-25 17:48:04
Donidalorsen is an antisense oligonucleotide designed to reduce the production of prekallikrein (PKK). PKK plays an important role in the activation of inflammatory mediators associated with acute attacks of Hereditary angioedema (HAE).

Name	Donidalorsen

Description	Donidalorsen is an antisense oligonucleotide designed to reduce the production of prekallikrein (PKK). PKK plays an important role in the activation of inflammatory mediators associated with acute attacks of Hereditary angioedema (HAE).
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Fijen LM, Riedl MA, Bordone L, et al. Inhibition of Prekallikrein for Hereditary Angioedema. N Engl J Med. 2022;386(11):1026-1033. [2]. Valerieva A, Longhurst HJ. Treatment of hereditary angioedema-single or multiple pathways to the rescue. Front Allergy. 2022;3:952233.

Molecular Formula	C₂₉₆H₄₃₅N₈₃O₁₅₁P₂₀S₁₅
Molecular Weight	8672.64