2687245-05-0

2687245-05-0 structure

Name: EBOV/MARV-IN-3
Chemical Name: EBOV/MARV-IN-3
CAS Number: 2687245-05-0
Molecular Formula: C₂₇H₂₉F₃N₂O₆
Molecular Weight: 534.52
Catalog: Signaling Pathways Anti-infection Filovirus
Create Date: 2023-06-03 17:59:26
Modify Date: 2024-09-19 11:07:57
EBOV/MARV-IN-3 (compound 32) is a potent EBOV and MARV inhibitor with IC50 values of 0.5, 1.2 µM, respectively. EBOV/MARV-IN-3 binds to the hydrophobic pocket close to EBOV Y517. EBOV/MARV-IN-3 shows antiviral activity[1].

Name	EBOV/MARV-IN-3

Description	EBOV/MARV-IN-3 (compound 32) is a potent EBOV and MARV inhibitor with IC50 values of 0.5, 1.2 µM, respectively. EBOV/MARV-IN-3 binds to the hydrophobic pocket close to EBOV Y517. EBOV/MARV-IN-3 shows antiviral activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Filovirus
Target	IC50: 0.5 µM (EBOV); 1.2 µM (MARV)[1]
References	[1]. Gao Y, et al. Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein. Eur J Med Chem. 2020 Oct 15;204:112595.

Molecular Formula	C₂₇H₂₉F₃N₂O₆
Molecular Weight	534.52