1643757-72-5

1643757-72-5 structure

Name: Fosnetupitant chloride monohydrochloride
Chemical Name: Fosnetupitant chloride monohydrochloride
CAS Number: 1643757-72-5
Molecular Formula: C₃₁H₃₇Cl₂F₆N₄O₅P
Molecular Weight: 761.52
Catalog: Signaling Pathways GPCR/G Protein Neurokinin Receptor
Create Date: 2023-09-18 19:18:23
Modify Date: 2024-01-12 13:09:01
Fosnetupitant chloride monohydrochloride (Pronetupitant chloride monohydrochloride) is an NK1 antagonist with pKi values of 9.5, 6.1 for human NK1 and NK3 receptor, respectively. Fosnetupitant chloride monohydrochloride is a methylene phosphate prodrug of Netupitant[1].

Name	Fosnetupitant chloride monohydrochloride

Description	Fosnetupitant chloride monohydrochloride (Pronetupitant chloride monohydrochloride) is an NK1 antagonist with pKi values of 9.5, 6.1 for human NK1 and NK3 receptor, respectively. Fosnetupitant chloride monohydrochloride is a methylene phosphate prodrug of Netupitant[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
Target	hNK1:9.5 (pKi) hNK3:6.1 (pKi)
References	[1]. Ruzza C, et al. In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant. Peptides. 2015 Jul;69:26-32.

Molecular Formula	C₃₁H₃₇Cl₂F₆N₄O₅P
Molecular Weight	761.52