651782-02-4

651782-02-4 structure

Name: Hainantoxin-IV
Chemical Name: Hainantoxin-IV
CAS Number: 651782-02-4
Molecular Formula: C₁₆₆H₂₅₇N₅₃O₅₀S₆
Molecular Weight: 3987.53
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2023-09-20 18:10:00
Modify Date: 2024-04-09 10:47:30
Hainantoxin-IV is a specific antagonist of Sodium Channel, targeting to tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels. His28 and Lys32 are the key resiudes of Hainantoxin-IV for binding with target, while Hainantoxin-IV adopts an inhibitor cystine knot motif[1].

Name	Hainantoxin-IV

Description	Hainantoxin-IV is a specific antagonist of Sodium Channel, targeting to tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels. His28 and Lys32 are the key resiudes of Hainantoxin-IV for binding with target, while Hainantoxin-IV adopts an inhibitor cystine knot motif[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
References	[1]. Liu Y, et al. A positively charged surface patch is important for hainantoxin-IV binding to voltage-gated sodium channels. J Pept Sci. 2012 Oct;18(10):643-9.

Molecular Formula	C₁₆₆H₂₅₇N₅₃O₅₀S₆
Molecular Weight	3987.53