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2923366-36-1

2923366-36-1 structure

2923366-36-1 structure

Name: hBChE-IN-2
Chemical Name: hBChE-IN-2
CAS Number: 2923366-36-1
Molecular Formula: C₂₇H₃₆N₄O₃
Molecular Weight: 464.60
Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
Create Date: 2023-09-23 12:21:49
Modify Date: 2024-01-27 18:19:23
hBChE-IN-2 (compound 15d) is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist. hBChE-IN-2 has neuroprotection activities[1].

Name	hBChE-IN-2

Description	hBChE-IN-2 (compound 15d) is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist. hBChE-IN-2 has neuroprotection activities[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor Signaling Pathways >> Neuronal Signaling >> AChE
Target	hBCHE:0.67 μM (IC50) hCB2-R:0.78 μM (IC50)
References	[1]. Philipp Spatz, et al. Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer's Disease Mouse Model. J Med Chem. 2023 May 11;66(9):6414-6435.

Molecular Formula	C₂₇H₃₆N₄O₃
Molecular Weight	464.60

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