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2640819-75-4

2640819-75-4 structure

2640819-75-4 structure

Name: JG-23
Chemical Name: JG-23
CAS Number: 2640819-75-4
Molecular Formula: C₁₉H₁₆ClN₃OS₂
Molecular Weight: 401.93
Catalog: Research Areas Neurological Disease
Create Date: 2023-09-19 08:39:28
Modify Date: 2024-08-13 11:43:41
JG-23 is a 4-chloro modified analog with ability to promote t-tau degradation. JG-23 exhibits good metabolic stability with a long T1/2 value (36 min) in mouse liver microsome assays[1].

Name	JG-23

Description	JG-23 is a 4-chloro modified analog with ability to promote t-tau degradation. JG-23 exhibits good metabolic stability with a long T1/2 value (36 min) in mouse liver microsome assays[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Shao H, et al. Inhibitors of heat shock protein 70 (Hsp70) with enhanced metabolic stability reduce tau levels. Bioorg Med Chem Lett. 2021 Jun 1;41:128025.

Molecular Formula	C₁₉H₁₆ClN₃OS₂
Molecular Weight	401.93

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