242487-82-7

242487-82-7 structure

Name: S1R agonist 1 hydrochloride
Chemical Name: S1R agonist 1 hydrochloride
CAS Number: 242487-82-7
Molecular Formula: C₂₀H₂₆ClNO
Molecular Weight: 331.88
Catalog: Signaling Pathways GPCR/G Protein Sigma Receptor
Create Date: 2023-09-22 09:29:01
Modify Date: 2024-01-02 17:36:56
S1R agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively. S1R agonist 1 hydrochloride exhibits neuroprotection against ROS and NMDA-induced neurotoxicity[1].

Name	S1R agonist 1 hydrochloride

Description	S1R agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively. S1R agonist 1 hydrochloride exhibits neuroprotection against ROS and NMDA-induced neurotoxicity[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Sigma Receptor
Target	Ki: 0.93 nM and 72 nM for S1R and S2R[1]
References	[1]. Linciano P, et al. Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents. Eur J Med Chem. 2023 Mar 5;249:115163.

Molecular Formula	C₂₀H₂₆ClNO
Molecular Weight	331.88