134052-73-6

134052-73-6 structure

Name: (S)-4CPG
Chemical Name: (s)-4-carboxyphenylglycine
CAS Number: 134052-73-6
Molecular Formula: C₉H₉NO₄
Molecular Weight: 195.17
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2018-08-02 17:13:57
Modify Date: 2024-01-18 12:09:40
(S)-4CPG ((S)-4-Carboxyphenylglycine) is a potent mGluR2 agonist. (S)-4CPG reduces hyperalgesia and allodynia associated with sciatic nerve contraction injury in rats. (S)-4CPG can be used in research on neurological diseases[1][2].

Name	(s)-4-carboxyphenylglycine

Description	(S)-4CPG ((S)-4-Carboxyphenylglycine) is a potent mGluR2 agonist. (S)-4CPG reduces hyperalgesia and allodynia associated with sciatic nerve contraction injury in rats. (S)-4CPG can be used in research on neurological diseases[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
References	[1]. Hayashi Y, et al. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J Neurosci. 1994 May;14(5 Pt 2):3370-7. [2]. Fisher K, et al. Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats. Pain. 1998 Jul;77(1):59-66.