238074-89-0

238074-89-0 structure
238074-89-0 structure
  • Name: CH-1504
  • Chemical Name: CH-1504
  • CAS Number: 238074-89-0
  • Molecular Formula: C23H23N5O5
  • Molecular Weight: 449.46
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  • CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.

Name CH-1504
Description CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.
References 1. Keystone EC, Shirinsky VS, Simon LS, Pedder S, Hewitt LA; CH-1504 Study Group.. Efficacy and safety of CH-1504, a metabolically stable antifolate, in patients with active rheumatoid arthritis: results of a phase II multicenter randomized study. J Rheumatol. 2011 Sep;38(9):1875-83. doi: 10.3899/jrheum.101038. PubMed PMID: 21724705.
Molecular Formula C23H23N5O5
Molecular Weight 449.46