2906099-98-5

2906099-98-5 structure

Name: DprE1-IN-9
Chemical Name: DprE1-IN-9
CAS Number: 2906099-98-5
Molecular Formula: C₂₂H₂₅F₃N₄O₂
Molecular Weight: 434.45
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2024-10-01 15:13:23
Modify Date: 2024-10-01 15:13:23
DprE1-IN-9 (compound B18) is an effective reversible DprE1 inhibitor and can bind to the receptor cavity of DprE1. DprE1-IN-9 shows strong antimycobacterial activity not only against non-pathogenic strain H37Ra (MIC=0.18 µg/mL) but also against pathogenic H37Rv and the clinical MDR and XDR isolates[1].

Name	DprE1-IN-9

Description	DprE1-IN-9 (compound B18) is an effective reversible DprE1 inhibitor and can bind to the receptor cavity of DprE1. DprE1-IN-9 shows strong antimycobacterial activity not only against non-pathogenic strain H37Ra (MIC=0.18 µg/mL) but also against pathogenic H37Rv and the clinical MDR and XDR isolates[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Wang Xiang, et al. Discovery of novel reversible inhibitor of DprE1 based on benzomorpholine for the treatment of tuberculosis. Microbiol Spectr. 2023 Sep 12:e0472122.

Molecular Formula	C₂₂H₂₅F₃N₄O₂
Molecular Weight	434.45