2922929-62-0

2922929-62-0 structure

Name: ER degrader 6
Chemical Name: ER degrader 6
CAS Number: 2922929-62-0
Molecular Formula: C₃₃H₃₄FN₃O₅SSe
Molecular Weight: 682.66
Catalog: Research Areas Cancer
Create Date: 2023-12-07 11:24:49
Modify Date: 2026-07-16 16:35:16
ER degrader 6 (compound 35s) is a potent Estrogen Receptor (ER)α degrader. ER degrader 6 disrupts the microtubule network by restraining tubulin polymerization. ER degrader 6 suppresses tumor growth without noticeable poisonousness[1].

Name	ER degrader 6
Synonyms	ER deader 6 Selenocyanic acid, 6-[[4-[6-[[ethyl(2-fluorophenyl)amino]sulfonyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]ht-2-en-2-yl]phenyl]amino]-6-oxohexyl ester

Description	ER degrader 6 (compound 35s) is a potent Estrogen Receptor (ER)α degrader. ER degrader 6 disrupts the microtubule network by restraining tubulin polymerization. ER degrader 6 suppresses tumor growth without noticeable poisonousness[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Cancer
Target	ERα
References	[1]. Deng X, et al. Identification of Novel Dual-Target Estrogen Receptor α Degraders with Tubulin Inhibitory Activity for the Treatment of Endocrine-Resistant Breast Cancer. J Med Chem. 2023 Aug 24;66(16):11094-11117.

Molecular Formula	C₃₃H₃₄FN₃O₅SSe
Molecular Weight	682.66