2975602-78-7

2975602-78-7 structure

Name: PD-1/PD-L1-IN-33
Chemical Name: PD-1/PD-L1-IN-33
CAS Number: 2975602-78-7
Molecular Formula: C₂₆H₂₇N₅O
Molecular Weight: 425.53
Catalog: Signaling Pathways Immunology/Inflammation PD-1/PD-L1
Create Date: 2023-11-08 09:22:22
Modify Date: 2024-01-17 12:11:21
PD-1/PD-L1-IN-33 (Compound N11) is a PD-1/PD-L1 inhibitor. PD-1/PD-L1-IN-33 inhibits PD-1 and PD-L1 interaction with an IC50: 6.3 nM. PD-1/PD-L1-IN-33 promotes T-cell proliferation, activation, and infiltration into tumor spheres. PD-1/PD-L1-IN-33 has immunomodulatory and anticancer activity[1].

Name	PD-1/PD-L1-IN-33

Description	PD-1/PD-L1-IN-33 (Compound N11) is a PD-1/PD-L1 inhibitor. PD-1/PD-L1-IN-33 inhibits PD-1 and PD-L1 interaction with an IC50: 6.3 nM. PD-1/PD-L1-IN-33 promotes T-cell proliferation, activation, and infiltration into tumor spheres. PD-1/PD-L1-IN-33 has immunomodulatory and anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
References	[1]. Yangyang Meng, et al. Novel 4-Arylindolines Containing a Pyrido[3,2-d]pyrimidine Moiety as the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction Inhibitors for Tumor Immunotherapy. J. Med. Chem. 2023.

Molecular Formula	C₂₆H₂₇N₅O
Molecular Weight	425.53