2230826-33-0

2230826-33-0 structure

Name: (R,S,S)-VH032
Chemical Name: (R,S,S)-VH032
CAS Number: 2230826-33-0
Molecular Formula: C₂₂H₃₀N₄O₃S
Molecular Weight: 430.56
Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
Create Date: 2024-03-15 07:46:58
Modify Date: 2025-08-26 15:21:26
(R,S,S)-VH032 is Ligand for E3 Ligase used in the synthesis of PROTACs. VH032 is a VHL ligand and VHL/HIF-1α interaction inhibitor that recruits von Hippel-Lindau (VHL) proteins. (R,S,S)-VH032 synthesizes the tau-targeting small molecule PROTAC C004019 (HY-138669)[1].

Name	(R,S,S)-VH032

Description	(R,S,S)-VH032 is Ligand for E3 Ligase used in the synthesis of PROTACs. VH032 is a VHL ligand and VHL/HIF-1α interaction inhibitor that recruits von Hippel-Lindau (VHL) proteins. (R,S,S)-VH032 synthesizes the tau-targeting small molecule PROTAC C004019 (HY-138669)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
Target	VHL[1]
References	[1]. Wang W, et al. A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models. Theranostics. 2021 Mar 11;11(11):5279-5295.