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3572-74-5

3572-74-5 structure
3572-74-5 structure
  • Name: moxastine
  • Chemical Name: 2-(1,1-Diphenylethoxy)-N,N-dimethylethanamine
  • CAS Number: 3572-74-5
  • Molecular Formula: C18H23NO
  • Molecular Weight: 269.38100
  • Create Date: 2018-05-13 08:00:00
  • Modify Date: 2024-01-07 18:06:25

Name 2-(1,1-Diphenylethoxy)-N,N-dimethylethanamine
Synonyms Spofa 325
Theadrylettae
Mephenhydramine
Mephenhydraminum
Moxastine
Therdryl
Moxastin
Density 1.013g/cm3
Boiling Point 357.5ºC at 760mmHg
Molecular Formula C18H23NO
Molecular Weight 269.38100
Flash Point 105.5ºC
Exact Mass 269.17800
PSA 12.47000
LogP 3.52830
Index of Refraction 1.542

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KR6715000
CHEMICAL NAME :
Ethylamine, 2-(1,1-diphenylethoxy)-N,N-dimethyl-
CAS REGISTRY NUMBER :
3572-74-5
BEILSTEIN REFERENCE NO. :
1981628
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C18-H23-N-O
MOLECULAR WEIGHT :
269.42
WISWESSER LINE NOTATION :
1XR&R&O2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
95 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 2,323,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
43 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,189,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
110 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,189,1954 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2100 mg/kg/6W-I
TOXIC EFFECTS :
Liver - fatty liver degeneration
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,531,1961
HS Code 2922199090

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3572-74-5 structure

3572-74-5

Literature: Protiva et al. Chemicke Listy, 1949 , vol. 43, p. 257,260 Chem.Abstr., 1951 , p. 577

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3572-74-5 structure

3572-74-5

Literature: Seidlova,V. et al. Collection of Czechoslovak Chemical Communications, 1971 , vol. 36, p. 299 - 303
Precursor  2

DownStream  0

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%