1997158-25-4

1997158-25-4 structure

Name: AChE/BuChE-IN-4
Chemical Name: 2,4-Pyrimidinediamine, N4-[[1-(phenylmethyl)-4-piperidinyl]methyl]-
CAS Number: 1997158-25-4
Molecular Formula: C₁₇H₂₃N₅
Molecular Weight: 297.4
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2024-01-13 19:18:34
Modify Date: 2024-01-13 19:18:34
AChE/BuChE-IN-4(compound 4a) is aorally activeandbrain-penetrantmultitarget-directedAChE/BuChEinhibitor againstAChEandBuChE, with theIC50of 2.08 and 7.41 μM[1].

Name	2,4-Pyrimidinediamine, N4-[[1-(phenylmethyl)-4-piperidinyl]methyl]-

Description	AChE/BuChE-IN-4(compound 4a) is aorally activeandbrain-penetrantmultitarget-directedAChE/BuChEinhibitor againstAChEandBuChE, with theIC50of 2.08 and 7.41 μM[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	2.08 and 7.41 μM([1]
References	[1]. Conceição RAD, et al. Structure-based design of new N-benzyl-piperidine derivatives as multitarget-directed AChE/BuChE inhibitors for Alzheimer's disease [published online ahead of print, 2023 Oct 5]. J Cell Biochem. 2023;10.1002/jcb.30483.

Molecular Formula	C₁₇H₂₃N₅
Molecular Weight	297.4