2739866-40-9

2739866-40-9 structure

2739866-40-9 structure

Name: ALK-IN-27
Chemical Name: ALK-IN-27
CAS Number: 2739866-40-9
Molecular Formula: C₂₃H₂₂ClFN₆O
Molecular Weight: 452.91
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ALK
Create Date: 2024-01-08 19:14:42
Modify Date: 2024-01-08 19:14:42
ALK-IN-27 (compound 1) is a potent ALK inhibitor. ALK-IN-27 shows antitumor activity. ALK-IN-27 has an IC50 of 2.7 nM for Ba/F3 CLIP1-LTK cell[1].

Name	ALK-IN-27

Description	ALK-IN-27 (compound 1) is a potent ALK inhibitor. ALK-IN-27 shows antitumor activity. ALK-IN-27 has an IC50 of 2.7 nM for Ba/F3 CLIP1-LTK cell[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK
References	[1]. Jennifer Anne Green, et al. Methods of treating solid tumor using (19r)-5-chloro-3-ethyl-16-fluoro-10,19-dimethyl-20-oxa-3,4,10,11,23-pentaazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(24),2(6),4,8,11,13,15,17,21(25),22-decaen-22-amine. WO2023196910A1.

Molecular Formula	C₂₃H₂₂ClFN₆O
Molecular Weight	452.91