2413029-40-8
2413029-40-8 structure
- Name: EGFR-IN-89
- Chemical Name: EGFR-IN-89
- CAS Number: 2413029-40-8
- Molecular Formula: C26H31FN8O2S
- Molecular Weight: 538.64
- Catalog: Signaling Pathways JAK/STAT Signaling EGFR
- Create Date: 2024-01-08 12:34:23
- Modify Date: 2025-08-24 13:12:00
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EGFR-IN-89 (compound 13k) is a potent, fourth-generation EGFR mutation inhibitor with an IC50 of 10.1 nM against Del19/T790M/C797S mutations. EGFR-IN-89 shows higher selectivity over wild type[1].
| Name | EGFR-IN-89 |
|---|
| Description | EGFR-IN-89 (compound 13k) is a potent, fourth-generation EGFR mutation inhibitor with an IC50 of 10.1 nM against Del19/T790M/C797S mutations. EGFR-IN-89 shows higher selectivity over wild type[1]. |
|---|---|
| Related Catalog | |
| Target |
EGFR19del/TM/CS:10.1 nM (IC50) |
| References |
| Molecular Formula | C26H31FN8O2S |
|---|---|
| Molecular Weight | 538.64 |