Shanghai Nianxing Industrial Co., Ltd
China
Product Name: FAK-IN-14
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Purity: 98.0%
Stocking Period: 10 Day
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2766666-22-0

2766666-22-0 structure

2766666-22-0 structure

Name: FAK-IN-14
Chemical Name: FAK-IN-14
CAS Number: 2766666-22-0
Molecular Formula: C₂₁H₂₄BrN₇OS
Molecular Weight: 502.43
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FAK
Create Date: 2024-04-02 14:17:45
Modify Date: 2024-04-02 14:17:45
FAK-IN-14 (compound 8d) is a focal adhesion kinase(FAK) inhibitor with an IC50 value of 0.2438 nM. FAK-IN-14 induces U87-MG cell early apoptosis and arrest the cell at the G2/M phase[1].

Name	FAK-IN-14

Description	FAK-IN-14 (compound 8d) is a focal adhesion kinase(FAK) inhibitor with an IC50 value of 0.2438 nM. FAK-IN-14 induces U87-MG cell early apoptosis and arrest the cell at the G2/M phase[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FAK
References	[1]. Zhiwu Long, et al. Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors. Bioorg Chem. 2023.

Molecular Formula	C₂₁H₂₄BrN₇OS
Molecular Weight	502.43

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