Shanghai Nianxing Industrial Co., Ltd
China
Product Name: HC-5404
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2247396-91-2

2247396-91-2 structure

2247396-91-2 structure

Name: HC-5404
Chemical Name: HC-5404
CAS Number: 2247396-91-2
Molecular Formula: C₂₄H₂₄F₂N₄O₃
Molecular Weight: 454.47
Catalog: Signaling Pathways Cell Cycle/DNA Damage PERK
Create Date: 2023-12-19 13:52:47
Modify Date: 2025-09-05 11:34:36
HC-5404 is a potent and selective PERK inhibitor. HC-5404 has orally activity. HC-5404 significantly blocks metastasis via killing quiescent/slow-cycling ISRhigh[1][2].

Name	HC-5404

Description	HC-5404 is a potent and selective PERK inhibitor. HC-5404 has orally activity. HC-5404 significantly blocks metastasis via killing quiescent/slow-cycling ISRhigh[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> PERK
References	[1]. Michael E Stokes, et al. PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors. Clin Cancer Res. 2023, 29, 3. [2]. Veronica Calvo, et al. A PERK-Specific Inhibitor Blocks Metastatic Progression by Limiting Integrated Stress Response-Dependent Survival of Quiescent Cancer Cells. Clin Cancer Res. 2023.

Molecular Formula	C₂₄H₂₄F₂N₄O₃
Molecular Weight	454.47

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.