769973-37-7

769973-37-7 structure

Name: Huwentoxin I
Chemical Name: Huwentoxin I
CAS Number: 769973-37-7
Molecular Formula: C₁₆₁H₂₄₆N₄₈O₄₄S₆
Molecular Weight: 3750.36
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2024-03-05 23:16:27
Modify Date: 2024-03-05 23:16:27
Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC50 values of 66.1 and 4.80 nM, respectively[1].

Name	Huwentoxin I

Description	Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC50 values of 66.1 and 4.80 nM, respectively[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
References	[1]. Wang M, et al. The effects of huwentoxin-I on the voltage-gated sodium channels of rat hippocampal and cockroach dorsal unpaired median neurons. Peptides. 2012 Mar;34(1):19-25.

Molecular Formula	C₁₆₁H₂₄₆N₄₈O₄₄S₆
Molecular Weight	3750.36