2569296-51-9

2569296-51-9 structure
2569296-51-9 structure
  • Name: MIPS-21335
  • Chemical Name: MIPS-21335
  • CAS Number: 2569296-51-9
  • Molecular Formula: C24H21N7O5
  • Molecular Weight: 487.47
  • Catalog: Signaling Pathways PI3K/Akt/mTOR PI4K
  • Create Date: 2023-12-21 14:21:35
  • Modify Date: 2024-01-08 07:36:45
  • MIPS-21335 is an PI3KC2α inhibitor (IC50: 7 nM). MIPS-21335 also inhibits PI3KC2β, p110α, p110β and p110δ (IC50: 0.043, 0.140, 0.386, 0.742 μM). MIPS-21335 has antithrombotic effect[1].

Name MIPS-21335
Description MIPS-21335 is an PI3KC2α inhibitor (IC50: 7 nM). MIPS-21335 also inhibits PI3KC2β, p110α, p110β and p110δ (IC50: 0.043, 0.140, 0.386, 0.742 μM). MIPS-21335 has antithrombotic effect[1].
Related Catalog
Target

7 nM (PI3KC2α)[1].

References

[1]. Selvadurai MV, et al. Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation. Sci Transl Med. 2020 Jul 22;12(553):eaar8430.  

Molecular Formula C24H21N7O5
Molecular Weight 487.47
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