2569296-51-9

2569296-51-9 structure

2569296-51-9 structure

Name: MIPS-21335
Chemical Name: MIPS-21335
CAS Number: 2569296-51-9
Molecular Formula: C₂₄H₂₁N₇O₅
Molecular Weight: 487.47
Catalog: Signaling Pathways PI3K/Akt/mTOR PI4K
Create Date: 2023-12-21 14:21:35
Modify Date: 2024-01-08 07:36:45
MIPS-21335 is an PI3KC2α inhibitor (IC50: 7 nM). MIPS-21335 also inhibits PI3KC2β, p110α, p110β and p110δ (IC50: 0.043, 0.140, 0.386, 0.742 μM). MIPS-21335 has antithrombotic effect[1].

Name	MIPS-21335

Description	MIPS-21335 is an PI3KC2α inhibitor (IC50: 7 nM). MIPS-21335 also inhibits PI3KC2β, p110α, p110β and p110δ (IC50: 0.043, 0.140, 0.386, 0.742 μM). MIPS-21335 has antithrombotic effect[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> PI3K/Akt/mTOR >> PI4K
Target	7 nM (PI3KC2α)[1].
References	[1]. Selvadurai MV, et al. Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation. Sci Transl Med. 2020 Jul 22;12(553):eaar8430.

Molecular Formula	C₂₄H₂₁N₇O₅
Molecular Weight	487.47