2272917-13-0
2272917-13-0 structure
- Name: NT-0796
- Chemical Name: NT-0796
- CAS Number: 2272917-13-0
- Molecular Formula: C23H27N3O4
- Molecular Weight: 409.48
- Catalog: Signaling Pathways Immunology/Inflammation NOD-like Receptor (NLR)
- Create Date: 2023-12-21 19:47:43
- Modify Date: 2026-07-01 09:43:16
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NT-0796 is a selective and CNS-penetrant NLRP3 inflammasome inhibitor with an IC50 of 0.32 nM in PBMC assay. NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795, the carboxylic acid active species. NT-0796 has the potential for neuroinflammatory diseases research[1].
| Name | NT-0796 |
|---|---|
| Synonyms |
Isopropyl (R)-2-(((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)cbamoyl)oxy)-3-(pyrimidin-2-yl)propanoate
Ruvonoflast (NT-0796) 2-Pyrimidinropanoic acid, α-[[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]oxy]-, 1-methylethyl ester, (αR) |
| Description | NT-0796 is a selective and CNS-penetrant NLRP3 inflammasome inhibitor with an IC50 of 0.32 nM in PBMC assay. NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795, the carboxylic acid active species. NT-0796 has the potential for neuroinflammatory diseases research[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C23H27N3O4 |
|---|---|
| Molecular Weight | 409.48 |