1006699-45-1

1006699-45-1 structure

1006699-45-1 structure

Name: PIM-IN-2
Chemical Name: PIM-IN-2
CAS Number: 1006699-45-1
Molecular Formula: C₁₉H₂₂N₄O₂
Molecular Weight: 338.40
Catalog: Signaling Pathways JAK/STAT Signaling Pim
Create Date: 2024-01-25 13:56:29
Modify Date: 2024-01-25 13:56:29
PIM-IN-2 (Pim-2) is a Pim kinases inhibitor (IC50 = 25 nM). PIM-IN-2 promotes cell survival, is antiapoptotic, and has exhibited an elevated level of expression in a variety of human tumors[1].

Name	PIM-IN-2

Description	PIM-IN-2 (Pim-2) is a Pim kinases inhibitor (IC50 = 25 nM). PIM-IN-2 promotes cell survival, is antiapoptotic, and has exhibited an elevated level of expression in a variety of human tumors[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> Pim
Target	PIM2
References	[1]. Qian K, et al. Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode [J]. Journal of medicinal chemistry, 2009, 52(7): 1814-1827.

Molecular Formula	C₁₉H₂₂N₄O₂
Molecular Weight	338.40