2883232-92-4
2883232-92-4 structure
- Name: BTK-IN-16
- Chemical Name: BTK-IN-16
- CAS Number: 2883232-92-4
- Molecular Formula: C15H14N4O2
- Molecular Weight: 282.3
- Create Date: 2024-03-14 21:09:34
- Modify Date: 2024-03-14 21:09:34
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BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to study various autoimmune diseases and cancers caused by BTK.
| Name | BTK-IN-16 |
|---|
| Description | BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to study various autoimmune diseases and cancers caused by BTK. |
|---|---|
| In Vivo | Studies on a mouse model (xid, X-linked immunodeficiency) have revealed the central role of BTK in B-cell BCR signal transduction, differentiation, and survival [1]. Further experiments using BTK-IN-16 on mature B cells suggest the involvement of BTK in B-cell malignancies and models of autoimmune diseases [1]. |
| References | 1. García-Merino A. Bruton's Tyrosine Kinase Inhibitors: A New Generation of Promising Agents for Multiple Sclerosis Therapy. Cells. 2021 Sep 27;10(10):2560. |
| Molecular Formula | C15H14N4O2 |
|---|---|
| Molecular Weight | 282.3 |