462100-05-6

462100-05-6 structure

Name: Cbz-NH-PEG3-CH2COOH
Chemical Name: 3-Oxo-1-phenyl-2,7,10,13-tetraoxa-4-azapentadecan-15-oic acid
CAS Number: 462100-05-6
Molecular Formula: C₁₆H₂₃NO₇
Molecular Weight: 341.356
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-08-15 12:56:16
Modify Date: 2025-09-10 16:39:59
Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	3-Oxo-1-phenyl-2,7,10,13-tetraoxa-4-azapentadecan-15-oic acid
Synonyms	2,7,10,13-Tetraoxa-4-azapentadecan-15-oic acid, 3-oxo-1-phenyl- 3-Oxo-1-phenyl-2,7,10,13-tetraoxa-4-azapentadecan-15-oic acid

Description	Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.