106134-33-2

106134-33-2 structure

Name: Ro 22-9194
Chemical Name: 2-amino-N-(2,6-dimethylphenyl)-N-(3-pyridin-3-ylpropyl)propanamide,dihydrochloride
CAS Number: 106134-33-2
Molecular Formula: C₁₉H₂₇Cl₂N₃O
Molecular Weight: 384.34300
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2016-01-23 16:08:23
Modify Date: 2024-02-18 09:32:57
Ro 22-9194 inhibits aggregation and thromboxane Az (TXA2) synthetase activity in rabbit and human platelets. Ro 22-9194 has a potent inhibitory action against various types of model arrhythmias. Ro 22-9194 has non-cholinergic cardiac depressant properties with its vasodilating action[1][2].

Name	2-amino-N-(2,6-dimethylphenyl)-N-(3-pyridin-3-ylpropyl)propanamide,dihydrochloride
Synonyms	Ro 22-9194

Description	Ro 22-9194 inhibits aggregation and thromboxane Az (TXA2) synthetase activity in rabbit and human platelets. Ro 22-9194 has a potent inhibitory action against various types of model arrhythmias. Ro 22-9194 has non-cholinergic cardiac depressant properties with its vasodilating action[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
References	[1]. M Murakami, et al. Cardiovascular effects of 2-amino-N-(2,6-dimethylphenyl)-N-[3-(3-pyridyl)propyl]propionamide dihydrochloride (Ro 22-9194) in the isolated, cross-perfused atrium of the dog. Jpn Heart J. 1990 Sep;31(5):731-9. [2]. I Kodama, et al. Electropharmacology of Ro 22-9194, a new antiarrhythmic agent. Gen Pharmacol. 1996 Jul;27(5):755-60.