135722-27-9

135722-27-9 structure

Name: S-14671
Chemical Name: N-[2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl]thiophene-2-carboxamide
CAS Number: 135722-27-9
Molecular Formula: C₂₂H₂₅N₃O₂S
Molecular Weight: 395.51800
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2017-12-24 17:24:57
Modify Date: 2023-01-18 23:25:27
S-14671 is a high-affinity 5-HT1A agonist (pKi=9.3). S-14671 can be used for research on neurological diseases, such as anti-anxiety, anti-depression, etc[1].

Name	N-[2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl]thiophene-2-carboxamide
Synonyms	4-((Thenoyl)-2-aminoethyl)-1-(7-methoxynaphthylpiperazine) N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}thiophene-2-carboxamide

Description	S-14671 is a high-affinity 5-HT1A agonist (pKi=9.3). S-14671 can be used for research on neurological diseases, such as anti-anxiety, anti-depression, etc[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT1A Receptor:9.3 (pKi)
References	[1]. Millan MJ, et al. S 14671: a novel naphthylpiperazine 5-HT1A agonist of high efficacy and exceptional in vivo potency. Eur J Pharmacol. 1991 Oct 15;203(2):319-22.