145819-92-7

145819-92-7 structure

Name: [[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathi olan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon ic acid
Chemical Name: [(2R,5S)-5-(6-amino-5-fluoro-2,4-dioxo-1H-pyrimidin-3-yl)-1,3-oxathiolan-2-yl]methyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid
CAS Number: 145819-92-7
Molecular Formula: C₈H₁₃FN₃O₁₂P₃S
Molecular Weight: 487.18600
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2017-01-27 21:10:19
Modify Date: 2024-02-15 17:27:21
Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427). Emtricitabine is a nucleoside reverse transcriptase inhibitor. Emtricitabine is antiretroviral agent for HIV and HBV infection[1][2].

Name	[(2R,5S)-5-(6-amino-5-fluoro-2,4-dioxo-1H-pyrimidin-3-yl)-1,3-oxathiolan-2-yl]methyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid

Description	Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427). Emtricitabine is a nucleoside reverse transcriptase inhibitor. Emtricitabine is antiretroviral agent for HIV and HBV infection[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Frasca K, et al. Emtricitabine triphosphate in dried blood spots is a predictor of viral suppression in HIV infection and reflects short-term adherence to antiretroviral therapy. J Antimicrob Chemother. 2019 May 1;74(5):1395-1401. [2]. Bang LM, et al. Emtricitabine: an antiretroviral agent for HIV infection. Drugs. 2003;63(22):2413-24; discussion 2425-6.