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1335210-23-5

1335210-23-5 structure
1335210-23-5 structure
  • Name: Dolutegravir intermediate-1
  • Chemical Name: 2,​5-​Pyridinedicarboxylic acid, 1-​(2,​2-​dimethoxyethyl)​-​1,​4-​dihydro-​3-​methoxy-​4-​oxo-​, 2-​methyl ester
  • CAS Number: 1335210-23-5
  • Molecular Formula: C13H17NO8
  • Molecular Weight: 315.276
  • Catalog: Pharmaceutical intermediate API intermediate
  • Create Date: 2018-02-09 08:00:00
  • Modify Date: 2024-01-03 02:15:20
  • Dolutegravir intermediate-1 is a novel synthetic intermediate of dolutegravir extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-l infection.

Name 2,​5-​Pyridinedicarboxylic acid, 1-​(2,​2-​dimethoxyethyl)​-​1,​4-​dihydro-​3-​methoxy-​4-​oxo-​, 2-​methyl ester
Synonyms 1-(2,2-Dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydro-3-pyridinecarboxylic acid
2,5-Pyridinedicarboxylic acid, 1-(2,2-dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-, 2-methyl ester
1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
Dolutegravir intermediate-1
1-(2,2-Dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-2,5-pyridinedicarboxylic acid 2-methyl ester
Description Dolutegravir intermediate-1 is a novel synthetic intermediate of dolutegravir extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-l infection.
Related Catalog
References

[1]. Sivaram Prasad, et al. Process for the preparation of dolutegravir . WO 2016125192 A2.

Density 1.4±0.1 g/cm3
Boiling Point 474.1±45.0 °C at 760 mmHg
Molecular Formula C13H17NO8
Molecular Weight 315.276
Flash Point 240.5±28.7 °C
Exact Mass 315.095428
PSA 113.29000
LogP -1.00
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.536
Storage condition 2-8℃