Name | 2,5-Pyridinedicarboxylic acid, 1-(2,2-dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-, 2-methyl ester |
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Synonyms |
1-(2,2-Dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydro-3-pyridinecarboxylic acid
2,5-Pyridinedicarboxylic acid, 1-(2,2-dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-, 2-methyl ester 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid Dolutegravir intermediate-1 1-(2,2-Dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-2,5-pyridinedicarboxylic acid 2-methyl ester |
Description | Dolutegravir intermediate-1 is a novel synthetic intermediate of dolutegravir extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-l infection. |
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Related Catalog | |
References |
[1]. Sivaram Prasad, et al. Process for the preparation of dolutegravir . WO 2016125192 A2. |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 474.1±45.0 °C at 760 mmHg |
Molecular Formula | C13H17NO8 |
Molecular Weight | 315.276 |
Flash Point | 240.5±28.7 °C |
Exact Mass | 315.095428 |
PSA | 113.29000 |
LogP | -1.00 |
Vapour Pressure | 0.0±2.5 mmHg at 25°C |
Index of Refraction | 1.536 |
Storage condition | 2-8℃ |