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402567-16-2

402567-16-2 structure
402567-16-2 structure
  • Name: Firategrast
  • Chemical Name: (2S)-2-[(2,6-difluorobenzoyl)amino]-3-[4-[4-(ethoxymethyl)-2,6-dimethoxyphenyl]phenyl]propanoic acid
  • CAS Number: 402567-16-2
  • Molecular Formula: C27H27F2NO6
  • Molecular Weight: 499.50300
  • Catalog: Signaling Pathways Cytoskeleton Integrin
  • Create Date: 2017-06-28 00:58:29
  • Modify Date: 2024-01-14 17:16:06
  • Firategrast is an orally bioavailable α4β1/α4β7 integrin antagonist.

Name (2S)-2-[(2,6-difluorobenzoyl)amino]-3-[4-[4-(ethoxymethyl)-2,6-dimethoxyphenyl]phenyl]propanoic acid
Synonyms Firategrast (USAN)
Firategrast
UNII-OJY3SK9H5F
Description Firategrast is an orally bioavailable α4β1/α4β7 integrin antagonist.
Related Catalog
Target

α4β1/α4β7[1]

In Vitro Firategrast is an orally bioavailable α4β1/α4β7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS)[1].
References

[1]. Grove RA, et al. Leukocyte counts in cerebrospinal fluid and blood following firategrast treatment in subjects with relapsing forms of multiple sclerosis. Eur J Neurol. 2013 Jul;20(7):1032-42.

Molecular Formula C27H27F2NO6
Molecular Weight 499.50300
Exact Mass 499.18100
PSA 97.58000
LogP 5.18600
Storage condition 2-8℃