35873-49-5

35873-49-5 structure

Name: 8-Cyclopentyl-1,3-dimethylxanthine
Chemical Name: 8-cyclopentyl-1,3-dimethyl-7H-purine-2,6-dione
CAS Number: 35873-49-5
Molecular Formula: C₁₂H₁₆N₄O₂
Molecular Weight: 248.28100
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2018-02-11 08:00:00
Modify Date: 2026-07-05 12:00:50
8-Cyclopentyl-1,3-dimethylxanthine (Compound 2a) is a selective adenosine A1 receptor antagonist with Kis of 10.9 nM and 1440 nM for A1 receptor and A2 receptor, respectively[1].

Name	8-cyclopentyl-1,3-dimethyl-7H-purine-2,6-dione
Synonyms	1,3-dimethyl-8-cyclopentylxanthine 8-CYCLOPENTYL-1,3-DIMETHYLXANTHINE T) (8-CYCLOPENTYLTHEOPHY T, NSC 8-CYCLOPENTYL-1,3-DIMETHYLXANTHINE 8-Cyclopentyl-1,3-dimethylxanthine, A1 adenosine rector antagonist 8-cyclopentyl-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione PD-116600 8-Cyclopentyl-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione 8-Cyclopentyl theophylline 8-CYCLOPENTYL-1,3-DIMETHYLXANTHINE ( 8-CYCLOPENTYLTHEOPHYLLINE)) 8-cyclopentyl-theophyllin 8-Cyclopentyl-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione 8-Cyclopentyl-1,3-dimethylxanthine, 10 mM in DMSO Xanthine,8-cyclopentyl-1,3-dimethyl T, 8-Cyclopentyltheophylline 8-Cyclopentyl-3,9-dihydro-1,3-diMethyl-1H-purine-2,6-dione cyclopentyl teophylline 8-Cyclopentyl-1,3-dimethylxanthine,8-Cyclopentyltheophylline, T Adenosine Rector,inhibit,Inhibitor,P1 rector,8 Cyclopentyl 1,3 dimethylxanthine,8Cyclopentyl1,3dimethylxanthine 1,3-Dimethyl-8-cyclopentyl-1H-purine-2,6(3H,7H)-dione 8-Cyclopentyltheophylline, T 1H-Purine-2,6-dione, 8-cyclopentyl-3,9-dihydro-1,3-dimethyl Theophylline,8-cyclopentyl 8-cyclopentyl-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione 8-Cyclopentyltheophylline CPT 8-CYCLOPENTYLTHEOPHYLLINE 8-T 8-cyclopentyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione

Description	8-Cyclopentyl-1,3-dimethylxanthine (Compound 2a) is a selective adenosine A1 receptor antagonist with Kis of 10.9 nM and 1440 nM for A1 receptor and A2 receptor, respectively[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	Ki: 10.9 nM (A1 receptor), 1440 nM (A2 receptor)[1]
References	[1]. K A Jacobson, et al. Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. J Med Chem. 1989 Aug;32(8):1873-9.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 14,1202,1971

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#06862

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XH5093600
HS Code	2933990090

Precursor 2
5440-00-6 3400-45-1
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%