Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: protheobromine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
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Email: enquiry@dycnchem.com

50-39-5

50-39-5 structure

Name: protheobromine
Chemical Name: 1-(2-hydroxypropyl)-3,7-dimethylpurine-2,6-dione
CAS Number: 50-39-5
Molecular Formula: C₁₀H₁₄N₄O₃
Molecular Weight: 238.24300
Catalog: API Antibiotics Penicillin
Create Date: 2018-08-28 20:08:07
Modify Date: 2025-08-25 17:15:51
Protheobromine is a cardiotonic and bronchodilator

Name	1-(2-hydroxypropyl)-3,7-dimethylpurine-2,6-dione
Synonyms	1-(2-Hydroxy-propyl)-3,7-dimethyl-3,7-dihydro-purin-2,6-dion Bonicor Theocor 1-<2-Hydroxy-propyl>-3,7-dimethyl-xanthin Pro-Cor Corodil Cordabromin Pantobromino Protheobromin Vascopil Cordaleromin Protheobromine 1-(2-hydroxy-propyl)-3,7-dimethyl-3,7-dihydro-purine-2,6-dione

Description	Protheobromine is a cardiotonic and bronchodilator
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. D M Aviado, Pharmacology of pentoxifylline, a hemorheologic agent for the treatment of intermittent claudication. Angiology. 1984 Jul;35(7):407-17.

Density	1.46g/cm3
Boiling Point	493.1ºC at 760mmHg
Molecular Formula	C₁₀H₁₄N₄O₃
Molecular Weight	238.24300
Flash Point	252ºC
Exact Mass	238.10700
PSA	82.05000
Index of Refraction	1.664

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XH2387000

CHEMICAL NAME :: Theobromine, 1-(2-hydroxypropyl)-

CAS REGISTRY NUMBER :: 50-39-5

BEILSTEIN REFERENCE NO. :: 0263332

LAST UPDATED :: 199706

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H14-N4-O3

MOLECULAR WEIGHT :: 238.28

WISWESSER LINE NOTATION :: T56 BN DN FNVNVJ B F H1YQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 780 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 6,457,1956

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 580 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 6,601,1956

HS Code	2933990090

10244-22-1

50-39-5

Literature: Cavallaro, Rosaria A.; Filocamo, Luigi; Galuppi, Annamaria; Galione, Antony; Brufani, Mario; Genazzani, Armando A. Journal of Medicinal Chemistry, 1999 , vol. 42, # 14 p. 2527 - 2534

83-67-0

50-39-5

Literature: Cavallaro, Rosaria A.; Filocamo, Luigi; Galuppi, Annamaria; Galione, Antony; Brufani, Mario; Genazzani, Armando A. Journal of Medicinal Chemistry, 1999 , vol. 42, # 14 p. 2527 - 2534

83-67-0

75-56-9

50-39-5

Literature: Roth Archiv der Pharmazie (Weinheim, Germany), 1959 , vol. 292, p. 234,236,237 Full Text Show Details Eckstein; Gorczyca Dissertationes Pharmaceuticae, 1962 , vol. 14, p. 393,-399 Chem.Abstr., 1963 , vol. 59, # 13978

2530-99-6

50-39-5

Literature: Eckstein; Gorczyca Dissertationes Pharmaceuticae, 1962 , vol. 14, p. 393,-399 Chem.Abstr., 1963 , vol. 59, # 13978

108-32-7

83-67-0

50-39-5

Literature: Fabbrini; Cencioni Farmaco, Edizione Scientifica, 1962 , vol. 17, p. 660,665

Precursor 5
10244-22-1 83-67-0 75-56-9 2530-99-6
108-32-7
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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