370881-96-2

370881-96-2 structure

Name: 2-Methyl-2-Propanyl 3,8-Diazabicyclo[4.2.0]Octane-3-Carboxylate
Chemical Name: 3-Boc-3,8-diazabicyclo[4.2.0]octane
CAS Number: 370881-96-2
Molecular Formula: C₁₁H₂₀N₂O₂
Molecular Weight: 212.289
Create Date: 2019-01-01 15:20:18
Modify Date: 2025-08-26 06:56:37

Name	3-Boc-3,8-diazabicyclo[4.2.0]octane
Synonyms	2-Methyl-2-propanyl (1S,6R)-3,8-diazabicyclo[4.2.0]octane-3-carboxylate 3,8-Diazabicyclo[4.2.0]octane-3-carboxylic acid, 1,1-dimethylethyl ester, (1S,6R)- 2-Methyl-2-propanyl 3,8-diazabicyclo[4.2.0]octane-3-carboxylate tert-butyl 3,8-diazabicyclo[4.2.0]octane-3-carboxylate cis-3-Boc-3,8-diazabicyclo[4,2,0]octane 3,8-Diazabicyclo[4.2.0]octane-3-carboxylic acid, 1,1-dimethylethyl ester

Density	1.1±0.1 g/cm3
Boiling Point	295.4±13.0 °C at 760 mmHg
Molecular Formula	C₁₁H₂₀N₂O₂
Molecular Weight	212.289
Flash Point	132.5±19.8 °C
Exact Mass	212.152481
PSA	41.57000
LogP	0.84
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.494

1293940-99-4

~75%

370881-96-2

Literature: JANSSEN PHARMACEUTICA NV; BRANSTETTER, Bryan, James; LETAVIC, Michael, A.; LY, Kiev, S.; RUDOLPH, Dale, A.; SAVALL, Brad, M.; SHAH, Chandravadan, R.; SHIREMAN, Brock, T. Patent: WO2011/50202 A1, 2011 ; Location in patent: Page/Page column 64-65 ; WO 2011/050202 A1

923956-64-3

~88%

370881-96-2

Literature: Frost, Jennifer M.; Bunnelle, William H.; Tietje, Karin R.; Anderson, David J.; Rueter, Lynne E.; Curzon, Peter; Surowy, Carol S.; Ji, Anquo; Daanen, Jerome F.; Kohlhaas, Kathy L.; Buckley, Michael J.; Henry, Rodger F.; Dyhring, Tino; Ahring, Philip K.; Meyer, Michael D. Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7843 - 7853