CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
AK8380000
-
CHEMICAL NAME :
-
Acetohydroxamic acid, N-(4-ethoxyphenyl)-
-
CAS REGISTRY NUMBER :
-
19315-64-1
-
LAST UPDATED :
-
199612
-
DATA ITEMS CITED :
-
8
-
MOLECULAR FORMULA :
-
C10-H13-N-O3
-
MOLECULAR WEIGHT :
-
195.24
-
WISWESSER LINE NOTATION :
-
QMV1R DO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
1200 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
702 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
15 gm/kg/73W-C
-
TOXIC EFFECTS :
-
Tumorigenic - neoplastic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
MUTATION DATA
-
TYPE OF TEST :
-
Morphological transformation
-
TEST SYSTEM :
-
Rodent - mouse Embryo
-
DOSE/DURATION :
-
100 ug/L
-
REFERENCE :
-
NCIMAV National Cancer Institute, Monograph. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) No.1- 1959- Volume(issue)/page/year: 58,21,1981 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 13,141,1977 IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 24,135,1980
|
